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Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse

Dysfunctional sarcoplasmic reticulum Ca(2+) handling is commonly observed in heart failure, and thought to contribute to arrhythmogenesis through several mechanisms. Some time ago we developed a cardiomyocyte-specific inducible SERCA2 knockout mouse, which is remarkable in the degree to which major...

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Detalles Bibliográficos
Autores principales:	Edwards, Andrew G., Mørk, Halvor, Stokke, Mathis K., Lipsett, David B., Sjaastad, Ivar, Richard, Sylvain, Sejersted, Ole M., Louch, William E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546347/ https://www.ncbi.nlm.nih.gov/pubmed/34712150 http://dx.doi.org/10.3389/fphys.2021.744730

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