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Red blood cells join the ranks as immune sentinels
New research shows that red blood cells express surface TLR9 that binds cell-free DNA, leading to erythrophagocytosis and innate immune activation.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546378/ https://www.ncbi.nlm.nih.gov/pubmed/34702989 http://dx.doi.org/10.1038/s41577-021-00648-2 |
| _version_ | 1784590183168999424 |
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| author | Minton, Kirsty |
| author_facet | Minton, Kirsty |
| author_sort | Minton, Kirsty |
| collection | PubMed |
| description | New research shows that red blood cells express surface TLR9 that binds cell-free DNA, leading to erythrophagocytosis and innate immune activation. |
| format | Online Article Text |
| id | pubmed-8546378 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-85463782021-10-26 Red blood cells join the ranks as immune sentinels Minton, Kirsty Nat Rev Immunol Research Highlight New research shows that red blood cells express surface TLR9 that binds cell-free DNA, leading to erythrophagocytosis and innate immune activation. Nature Publishing Group UK 2021-10-26 2021 /pmc/articles/PMC8546378/ /pubmed/34702989 http://dx.doi.org/10.1038/s41577-021-00648-2 Text en © Springer Nature Limited 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Research Highlight Minton, Kirsty Red blood cells join the ranks as immune sentinels |
| title | Red blood cells join the ranks as immune sentinels |
| title_full | Red blood cells join the ranks as immune sentinels |
| title_fullStr | Red blood cells join the ranks as immune sentinels |
| title_full_unstemmed | Red blood cells join the ranks as immune sentinels |
| title_short | Red blood cells join the ranks as immune sentinels |
| title_sort | red blood cells join the ranks as immune sentinels |
| topic | Research Highlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546378/ https://www.ncbi.nlm.nih.gov/pubmed/34702989 http://dx.doi.org/10.1038/s41577-021-00648-2 |
| work_keys_str_mv | AT mintonkirsty redbloodcellsjointheranksasimmunesentinels |