Metallothionein 2 activation by pravastatin reinforces epithelial integrity and ameliorates radiation-induced enteropathy

BACKGROUND: Radiotherapy or accidental exposure to ionizing radiation causes severe damage of healthy intestinal tissues. Intestinal barrier function is highly sensitive to ionizing radiation, and loss of epithelial integrity results in mucosal inflammation, bacterial translocation, and endotoxemia....

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Detalles Bibliográficos
Autores principales: Kwak, Seo Young, Jang, Won Il, Park, Seungwoo, Cho, Sang Sik, Lee, Seung Bum, Kim, Min-Jung, Park, Sunhoo, Shim, Sehwan, Jang, Hyosun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546423/
https://www.ncbi.nlm.nih.gov/pubmed/34688032
http://dx.doi.org/10.1016/j.ebiom.2021.103641

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