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Convergent olfactory trace amine-associated receptors detect biogenic polyamines with distinct motifs via a conserved binding site

Biogenic amines activate G-protein-coupled receptors (GPCRs) in the central nervous system in vertebrate animals. Several biogenic amines, when excreted, stimulate trace amine-associated receptors (TAARs), a group of GPCRs in the main olfactory epithelium, and elicit innate behaviors. How TAARs reco...

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Detalles Bibliográficos
Autores principales: Jia, Liang, Li, Shengju, Dai, Wenxuan, Guo, Lingna, Xu, Zhengrong, Scott, Anne M., Zhang, Zhe, Ren, Jianfeng, Zhang, Qinghua, Dexheimer, Thomas S., Chung-Davidson, Yu-Wen, Neubig, Richard R., Li, Qian, Li, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546428/
https://www.ncbi.nlm.nih.gov/pubmed/34600890
http://dx.doi.org/10.1016/j.jbc.2021.101268

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