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MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells
Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible MARCH8 expression, we show that MARCH8 did not alter susceptibility to influenza A virus (IAV)...
Autores principales: | Villalón-Letelier, Fernando, Brooks, Andrew G., Londrigan, Sarah L., Reading, Patrick C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546552/ https://www.ncbi.nlm.nih.gov/pubmed/34517760 http://dx.doi.org/10.1128/mBio.01484-21 |
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