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MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells

Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible MARCH8 expression, we show that MARCH8 did not alter susceptibility to influenza A virus (IAV)...

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Detalles Bibliográficos
Autores principales: Villalón-Letelier, Fernando, Brooks, Andrew G., Londrigan, Sarah L., Reading, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546552/
https://www.ncbi.nlm.nih.gov/pubmed/34517760
http://dx.doi.org/10.1128/mBio.01484-21

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