Methylation of PhoP by CheR Regulates Salmonella Virulence

The two-component system PhoP/PhoQ is essential for Salmonella enterica serovar Typhimurium virulence. Here, we report that PhoP is methylated extensively. Two consecutive glutamate (E) and aspartate (D)/E residues, i.e., E8/D9 and E107/E108, and arginine (R) 112 can be methylated. Individual mutati...

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Detalles Bibliográficos
Autores principales: Su, Yang, Li, Jianhui, Zhang, Wenting, Ni, Jinjing, Huang, Rui, Wang, Zuoqiang, Cheng, Sen, Wang, Yue, Tian, Zhixin, Zhou, Qiuxiang, Lin, Donghai, Wu, Wenjuan, Tang, Christoph M., Liu, Xiaoyun, Lu, Jie, Yao, Yu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546571/
https://www.ncbi.nlm.nih.gov/pubmed/34544273
http://dx.doi.org/10.1128/mBio.02099-21

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