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Building Biofoundry India: challenges and path forward

Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we se...

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Detalles Bibliográficos
Autores principales: Panda, Binay, Dhar, Pawan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546612/
https://www.ncbi.nlm.nih.gov/pubmed/34712840
http://dx.doi.org/10.1093/synbio/ysab015
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author Panda, Binay
Dhar, Pawan K
author_facet Panda, Binay
Dhar, Pawan K
author_sort Panda, Binay
collection PubMed
description Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we see the facility add a substantial value in supporting research, innovation and entrepreneurship. We describe three key areas of our focus, harnessing the potential of non-expressing parts of the sequenced genomes, using deep learning in pathway reconstruction and synthesising enzymes and metabolites. Toward the end, we describe specific challenges in building such facility in India and the path to mitigate some of those working with the other biofoundries worldwide.
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spelling pubmed-85466122021-10-27 Building Biofoundry India: challenges and path forward Panda, Binay Dhar, Pawan K Synth Biol (Oxf) Perspectives Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we see the facility add a substantial value in supporting research, innovation and entrepreneurship. We describe three key areas of our focus, harnessing the potential of non-expressing parts of the sequenced genomes, using deep learning in pathway reconstruction and synthesising enzymes and metabolites. Toward the end, we describe specific challenges in building such facility in India and the path to mitigate some of those working with the other biofoundries worldwide. Oxford University Press 2021-06-25 /pmc/articles/PMC8546612/ /pubmed/34712840 http://dx.doi.org/10.1093/synbio/ysab015 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Perspectives
Panda, Binay
Dhar, Pawan K
Building Biofoundry India: challenges and path forward
title Building Biofoundry India: challenges and path forward
title_full Building Biofoundry India: challenges and path forward
title_fullStr Building Biofoundry India: challenges and path forward
title_full_unstemmed Building Biofoundry India: challenges and path forward
title_short Building Biofoundry India: challenges and path forward
title_sort building biofoundry india: challenges and path forward
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546612/
https://www.ncbi.nlm.nih.gov/pubmed/34712840
http://dx.doi.org/10.1093/synbio/ysab015
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