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Building Biofoundry India: challenges and path forward
Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we se...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546612/ https://www.ncbi.nlm.nih.gov/pubmed/34712840 http://dx.doi.org/10.1093/synbio/ysab015 |
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author | Panda, Binay Dhar, Pawan K |
author_facet | Panda, Binay Dhar, Pawan K |
author_sort | Panda, Binay |
collection | PubMed |
description | Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we see the facility add a substantial value in supporting research, innovation and entrepreneurship. We describe three key areas of our focus, harnessing the potential of non-expressing parts of the sequenced genomes, using deep learning in pathway reconstruction and synthesising enzymes and metabolites. Toward the end, we describe specific challenges in building such facility in India and the path to mitigate some of those working with the other biofoundries worldwide. |
format | Online Article Text |
id | pubmed-8546612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-85466122021-10-27 Building Biofoundry India: challenges and path forward Panda, Binay Dhar, Pawan K Synth Biol (Oxf) Perspectives Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we see the facility add a substantial value in supporting research, innovation and entrepreneurship. We describe three key areas of our focus, harnessing the potential of non-expressing parts of the sequenced genomes, using deep learning in pathway reconstruction and synthesising enzymes and metabolites. Toward the end, we describe specific challenges in building such facility in India and the path to mitigate some of those working with the other biofoundries worldwide. Oxford University Press 2021-06-25 /pmc/articles/PMC8546612/ /pubmed/34712840 http://dx.doi.org/10.1093/synbio/ysab015 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Perspectives Panda, Binay Dhar, Pawan K Building Biofoundry India: challenges and path forward |
title | Building Biofoundry India: challenges and path forward |
title_full | Building Biofoundry India: challenges and path forward |
title_fullStr | Building Biofoundry India: challenges and path forward |
title_full_unstemmed | Building Biofoundry India: challenges and path forward |
title_short | Building Biofoundry India: challenges and path forward |
title_sort | building biofoundry india: challenges and path forward |
topic | Perspectives |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546612/ https://www.ncbi.nlm.nih.gov/pubmed/34712840 http://dx.doi.org/10.1093/synbio/ysab015 |
work_keys_str_mv | AT pandabinay buildingbiofoundryindiachallengesandpathforward AT dharpawank buildingbiofoundryindiachallengesandpathforward |