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CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
Azoles are the most commonly used clinical antifungal therapy and also play an important role in control of plant pathogens. Intrinsic resistance to the azole class of fungicides, which target lanosterol demethylase (CYP51), is observed in many fungal species; however, the mechanisms underpinning th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546618/ https://www.ncbi.nlm.nih.gov/pubmed/34607450 http://dx.doi.org/10.1128/mBio.01945-21 |