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Restoring Global Gene Regulation through Experimental Evolution Uncovers a NAP (Nucleoid-Associated Protein)-Like Behavior of Crp/Cap

How do hierarchical gene regulation networks evolve in bacteria? Nucleoid-associated proteins (NAPs) influence the overall structure of bacterial genomes, sigma factors and global transcription factors (TFs) control thousands of genes, and many operons are regulated by highly specific TFs that in tu...

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Detalles Bibliográficos
Autores principales:	Heyde, Sophia A. H., Frendorf, Pernille O., Lauritsen, Ida, Nørholm, Morten H. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546631/ https://www.ncbi.nlm.nih.gov/pubmed/34700380 http://dx.doi.org/10.1128/mBio.02028-21

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