Synchronous conjugation of i-motif DNA and therapeutic siRNA on the vertexes of tetrahedral DNA nanocages for efficient gene silence

The functionality of DNA biomacromolecules has been widely excavated, as therapeutic drugs, carriers, and functionalized modification derivatives. In this study, we developed a series of DNA tetrahedron nanocages (Td), via synchronous conjugating different numbers of i-(X) and therapeutic siRNA on f...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xiu, Xu, Xiang, Wu, Ziheng, Wu, Zhenghong, Qi, Xiaole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546665/
https://www.ncbi.nlm.nih.gov/pubmed/34729316
http://dx.doi.org/10.1016/j.apsb.2021.02.009

Ejemplares similares

Ejemplares similares