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High-Throughput Screen for Inhibitors of the Type IV Pilus Assembly ATPase PilB

The bacterial type IV pilus (T4P) is a prominent virulence factor in many significant human pathogens, some of which have become increasingly antibiotic resistant. Antivirulence chemotherapeutics are considered a promising alternative to antibiotics because they target the disease process instead of...

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Detalles Bibliográficos
Autores principales: Dye, Keane J., Vogelaar, Nancy J., Sobrado, Pablo, Yang, Zhaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546689/
https://www.ncbi.nlm.nih.gov/pubmed/33658276
http://dx.doi.org/10.1128/mSphere.00129-21