Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity

Malaria vaccine candidates based on live, attenuated sporozoites have led to high levels of protection. However, their efficacy critically depends on the sporozoites’ ability to reach and infect the host liver. Administration via mosquito inoculation is by far the most potent method for inducing imm...

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Detalles Bibliográficos
Autores principales: de Korne, C. M., Winkel, B. M. F., van Oosterom, M. N., Chevalley-Maurel, S., Houwing, H. M., Sijtsma, J. C., Azargoshasb, S., Baalbergen, E., Franke-Fayard, B. M. D., van Leeuwen, F. W. B., Roestenberg, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546700/
https://www.ncbi.nlm.nih.gov/pubmed/33827910
http://dx.doi.org/10.1128/mSphere.00218-21

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