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k-mer-Based Metagenomics Tools Provide a Fast and Sensitive Approach for the Detection of Viral Contaminants in Biopharmaceutical and Vaccine Manufacturing Applications Using Next-Generation Sequencing

Adventitious agent detection during the production of vaccines and biotechnology-based medicines is of critical importance to ensure the final product is free from any possible viral contamination. Increasing the speed and accuracy of viral detection is beneficial as a means to accelerate developmen...

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Detalles Bibliográficos
Autores principales: MacDonald, Madolyn L., Polson, Shawn W., Lee, Kelvin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546726/
https://www.ncbi.nlm.nih.gov/pubmed/33883263
http://dx.doi.org/10.1128/mSphere.01336-20

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