Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3

The TEA domain (TEAD) family proteins (TEAD1‒4) are essential transcription factors that control cell differentiation and organ size in the Hippo pathway. Although the sequences and structures of TEAD family proteins are highly conserved, each TEAD isoform has unique physiological and pathological f...

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Detalles Bibliográficos
Autores principales: Lu, Tian, Li, Yong, Lu, Wenchao, Spitters, TWGM, Fang, Xueyu, Wang, Jun, Cai, Simian, Gao, Jing, Zhou, Yanting, Duan, Zhe, Xiong, Huan, Liu, Liping, Li, Qi, Jiang, Hualiang, Chen, Kaixian, Zhou, Hu, Lin, Hua, Feng, Huijin, Zhou, Bing, Antos, Christopher L., Luo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546857/
https://www.ncbi.nlm.nih.gov/pubmed/34729310
http://dx.doi.org/10.1016/j.apsb.2021.04.015

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