Neutralizing Monoclonal Antibodies That Target the Spike Receptor Binding Domain Confer Fc Receptor-Independent Protection against SARS-CoV-2 Infection in Syrian Hamsters

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is the main target for neutralizing antibodies. These antibodies can be elicited through immunization or passively transferred as therapeutics in the form of convalescent-phase sera or monoclonal antibodies (MAbs). Potent...

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Detalles Bibliográficos
Autores principales: Su, Wen, Sia, Sin Fun, Schmitz, Aaron J., Bricker, Traci L., Starr, Tyler N., Greaney, Allison J., Turner, Jackson S., Mohammed, Bassem M., Liu, Zhuoming, Choy, Ka Tim, Darling, Tamarand L., Joshi, Astha, Cheng, Ka Man, Wong, Alvina Y. L., Harastani, Houda H., Nicholls, John M., Whelan, Sean P. J., Bloom, Jesse D., Yen, Hui-Ling, Ellebedy, Ali H., Boon, Adrianus C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546861/
https://www.ncbi.nlm.nih.gov/pubmed/34517754
http://dx.doi.org/10.1128/mBio.02395-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546861/
https://www.ncbi.nlm.nih.gov/pubmed/34517754
http://dx.doi.org/10.1128/mBio.02395-21

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