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Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification

In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and the...

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Autores principales: Martín, María, Cuevas, Javier, Cigarrán, Helena, Calvo, Juan, Morís, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546909/
https://www.ncbi.nlm.nih.gov/pubmed/34721669
http://dx.doi.org/10.15420/ecr.2021.09
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author Martín, María
Cuevas, Javier
Cigarrán, Helena
Calvo, Juan
Morís, César
author_facet Martín, María
Cuevas, Javier
Cigarrán, Helena
Calvo, Juan
Morís, César
author_sort Martín, María
collection PubMed
description In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and their incidence varies depending on the intensity of screening. Whether these phenomena are a surrogate for leaflet thrombosis reducing valve durability and increasing the risk of stroke is still a matter of debate. Uncertainty remains over the optimal antithrombotic therapy after TAVI and the best treatment strategy is still not confirmed. Ongoing and future trials will provide more evidence about the best strategy for the prevention and treatment of SLT.
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spelling pubmed-85469092021-10-29 Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification Martín, María Cuevas, Javier Cigarrán, Helena Calvo, Juan Morís, César Eur Cardiol Aortic Valve Stenosis In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and their incidence varies depending on the intensity of screening. Whether these phenomena are a surrogate for leaflet thrombosis reducing valve durability and increasing the risk of stroke is still a matter of debate. Uncertainty remains over the optimal antithrombotic therapy after TAVI and the best treatment strategy is still not confirmed. Ongoing and future trials will provide more evidence about the best strategy for the prevention and treatment of SLT. Radcliffe Cardiology 2021-09-24 /pmc/articles/PMC8546909/ /pubmed/34721669 http://dx.doi.org/10.15420/ecr.2021.09 Text en Copyright © 2021, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Aortic Valve Stenosis
Martín, María
Cuevas, Javier
Cigarrán, Helena
Calvo, Juan
Morís, César
Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
title Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
title_full Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
title_fullStr Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
title_full_unstemmed Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
title_short Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
title_sort transcatheter aortic valve implantation and subclinical and clinical leaflet thrombosis: multimodality imaging for diagnosis and risk stratification
topic Aortic Valve Stenosis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546909/
https://www.ncbi.nlm.nih.gov/pubmed/34721669
http://dx.doi.org/10.15420/ecr.2021.09
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