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Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification
In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Radcliffe Cardiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546909/ https://www.ncbi.nlm.nih.gov/pubmed/34721669 http://dx.doi.org/10.15420/ecr.2021.09 |
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author | Martín, María Cuevas, Javier Cigarrán, Helena Calvo, Juan Morís, César |
author_facet | Martín, María Cuevas, Javier Cigarrán, Helena Calvo, Juan Morís, César |
author_sort | Martín, María |
collection | PubMed |
description | In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and their incidence varies depending on the intensity of screening. Whether these phenomena are a surrogate for leaflet thrombosis reducing valve durability and increasing the risk of stroke is still a matter of debate. Uncertainty remains over the optimal antithrombotic therapy after TAVI and the best treatment strategy is still not confirmed. Ongoing and future trials will provide more evidence about the best strategy for the prevention and treatment of SLT. |
format | Online Article Text |
id | pubmed-8546909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Radcliffe Cardiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-85469092021-10-29 Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification Martín, María Cuevas, Javier Cigarrán, Helena Calvo, Juan Morís, César Eur Cardiol Aortic Valve Stenosis In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and their incidence varies depending on the intensity of screening. Whether these phenomena are a surrogate for leaflet thrombosis reducing valve durability and increasing the risk of stroke is still a matter of debate. Uncertainty remains over the optimal antithrombotic therapy after TAVI and the best treatment strategy is still not confirmed. Ongoing and future trials will provide more evidence about the best strategy for the prevention and treatment of SLT. Radcliffe Cardiology 2021-09-24 /pmc/articles/PMC8546909/ /pubmed/34721669 http://dx.doi.org/10.15420/ecr.2021.09 Text en Copyright © 2021, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly. |
spellingShingle | Aortic Valve Stenosis Martín, María Cuevas, Javier Cigarrán, Helena Calvo, Juan Morís, César Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification |
title | Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification |
title_full | Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification |
title_fullStr | Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification |
title_full_unstemmed | Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification |
title_short | Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification |
title_sort | transcatheter aortic valve implantation and subclinical and clinical leaflet thrombosis: multimodality imaging for diagnosis and risk stratification |
topic | Aortic Valve Stenosis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546909/ https://www.ncbi.nlm.nih.gov/pubmed/34721669 http://dx.doi.org/10.15420/ecr.2021.09 |
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