Quantifying the Evolutionary Constraints and Potential of Hepatitis C Virus NS5A Protein

RNA viruses, such as hepatitis C virus (HCV), influenza virus, and SARS-CoV-2, are notorious for their ability to evolve rapidly under selection in novel environments. It is known that the high mutation rate of RNA viruses can generate huge genetic diversity to facilitate viral adaptation. However,...

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Detalles Bibliográficos
Autores principales: Dai, Lei, Du, Yushen, Qi, Hangfei, Huber, Christian D., Chen, Dongdong, Zhang, Tian-Hao, Wu, Nicholas C., Wang, Ergang, Lloyd-Smith, James O., Sun, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546995/
https://www.ncbi.nlm.nih.gov/pubmed/33850042
http://dx.doi.org/10.1128/mSystems.01111-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546995/
https://www.ncbi.nlm.nih.gov/pubmed/33850042
http://dx.doi.org/10.1128/mSystems.01111-20

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