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Role of PRKDC in cancer initiation, progression, and treatment

The PRKDC gene encodes the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) protein. DNA-PKcs plays an important role in nonhomologous end joining (NHEJ) of DNA double-strand breaks (DSBs) and is also closely related to the establishment of central immune tolerance and the maintenance of ch...

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Detalles Bibliográficos
Autores principales:	Chen, Yu, Li, Yi, Xiong, Jiani, Lan, Bin, Wang, Xuefeng, Liu, Jun, Lin, Jing, Fei, Zhaodong, Zheng, Xiaobin, Chen, Chuanben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547028/ https://www.ncbi.nlm.nih.gov/pubmed/34702253 http://dx.doi.org/10.1186/s12935-021-02229-8

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