The role of patient-derived ovarian cancer organoids in the study of PARP inhibitors sensitivity and resistance: from genomic analysis to functional testing

Epithelial ovarian cancer (EOC) harbors distinct genetic features such as homologous recombination repair (HRR) deficiency, and therefore may respond to poly ADP-ribose polymerase inhibitors (PARPi). Over the past few years, PARPi have been added to the standard of care for EOC patients in both fron...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Mengyu, Wu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547054/
https://www.ncbi.nlm.nih.gov/pubmed/34702316
http://dx.doi.org/10.1186/s13046-021-02139-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547054/
https://www.ncbi.nlm.nih.gov/pubmed/34702316
http://dx.doi.org/10.1186/s13046-021-02139-7

Ejemplares similares