Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia

An increasing body of evidence suggests that impaired synapse development and function are associated with schizophrenia; however, the underlying molecular pathophysiological mechanism of the disease remains largely unclear. We conducted a family-based study combined with molecular and cellular anal...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kana, Kuriu, Toshihiko, Matsumura, Kensuke, Nagayasu, Kazuki, Tsurusaki, Yoshinori, Miyake, Noriko, Yamamori, Hidenaga, Yasuda, Yuka, Fujimoto, Michiko, Fujiwara, Mikiya, Baba, Masayuki, Kitagawa, Kohei, Takemoto, Tomoya, Gotoda-Nishimura, Nanaka, Takada, Tomohiro, Seiriki, Kaoru, Hayata-Takano, Atsuko, Kasai, Atsushi, Ago, Yukio, Kida, Satoshi, Takuma, Kazuhiro, Ono, Fumihito, Matsumoto, Naomichi, Hashimoto, Ryota, Hashimoto, Hitoshi, Nakazawa, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547217/
https://www.ncbi.nlm.nih.gov/pubmed/34697299
http://dx.doi.org/10.1038/s41398-021-01676-1

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