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Nitric Oxide–cGMP Pathway Modulation in an Experimental Model of Hypoxic Pulmonary Hypertension
Manipulation of nitric oxide (NO) may enable control of progression and treatment of pulmonary hypertension (PH). Several approaches may modulate the NO-cGMP pathway in vivo. Here, we investigate the effectiveness of 3 modulatory sites: (i) the amount of l-arginine; (ii) the size of plasma NO stores...
Autores principales: | Reinero, Melanie, Beghetti, Maurice, Tozzi, Piergiorgio, von Segesser, Ludwig K., Samaja, Michele, Milano, Giuseppina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547238/ https://www.ncbi.nlm.nih.gov/pubmed/33969747 http://dx.doi.org/10.1177/10742484211014162 |
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