Cargando…

Polygenic and multi locus heritability of alcoholism: Novel therapeutic targets to overcome psychological deficits

Detalles Bibliográficos
Autores principales:	Blum, Kenneth, Baron, David, Jalali, Rehan, Modestino, Edward J, Steinberg, Bruce, Elman, Igor, Badgaiyan, Rajendra D, Gold, Mark S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547332/ https://www.ncbi.nlm.nih.gov/pubmed/34707891 http://dx.doi.org/10.15761/JSIN.1000240

Ejemplares similares

Our evolved unique pleasure circuit makes humans different from apes: Reconsideration of data derived from animal studies
por: Blum, Kenneth, et al.
Publicado: (2018)

A Novel Precision Approach to Overcome the “Addiction Pandemic” by Incorporating Genetic Addiction Risk Severity (GARS) and Dopamine Homeostasis Restoration
por: Blum, Kenneth, et al.
Publicado: (2021)

Hypothesizing in the Face of the Opioid Crisis Coupling Genetic Addiction Risk Severity (GARS) Testing with Electrotherapeutic Nonopioid Modalities Such as H-Wave Could Attenuate Both Pain and Hedonic Addictive Behaviors
por: Gupta, Ashim, et al.
Publicado: (2022)

Metheamphetamine for Children: Are We Over or Under Dosing?
por: Blum, Kenneth, et al.
Publicado: (2023)

Reward Deficiency Syndrome (RDS) Surprisingly Is Evolutionary and Found Everywhere: Is It “Blowin’ in the Wind”?
por: Blum, Kenneth, et al.
Publicado: (2022)

Lyme and Dopaminergic Function: Hypothesizing Reduced Reward Deficiency Symptomatology by Regulating Dopamine Transmission
por: Blum, Kenneth, et al.
Publicado: (2017)

“Preaddiction” construct and reward deficiency syndrome: genetic link via dopaminergic dysregulation
por: Blum, Kenneth, et al.
Publicado: (2022)

Pro-dopamine regulator, KB220Z, attenuates hoarding and shopping behavior in a female, diagnosed with SUD and ADHD
por: McLaughlin, Thomas, et al.
Publicado: (2018)

Opioid and dopamine genes interact to predict precision naltrexone response in alcohol use disorder: Interpretation misfires
por: Blum, Kenneth, et al.
Publicado: (2021)

A Review of DNA Risk Alleles to Determine Epigenetic Repair of mRNA Expression to Prove Therapeutic Effectiveness in Reward Deficiency Syndrome (RDS): Embracing “Precision Behavioral Management”
por: Blum, Kenneth, et al.
Publicado: (2021)

Theorizing the Role of Dopaminergic Polymorphic Risk Alleles with Intermittent Explosive Disorder (IED), Violent/Aggressive Behavior and Addiction: Justification of Genetic Addiction Risk Severity (GARS) Testing
por: Modestino, Edward Justin, et al.
Publicado: (2022)

Offering a putative neurobiological “dopamine homeostatic” solution to overcome the perils of the reward deficiency syndrome pandemic: emergence of “precision behavioral management”
por: Blum, Kenneth, et al.
Publicado: (2022)

Precision Behavioral Management (PBM) and Cognitive Control as a Potential Therapeutic and Prophylactic Modality for Reward Deficiency Syndrome (RDS): Is There Enough Evidence?
por: Madigan, Margaret A., et al.
Publicado: (2022)

High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial
por: Moran, Mark, et al.
Publicado: (2021)

The effects of residential dual diagnosis treatment on alcohol abuse
por: Schoenthaler, Stephen J, et al.
Publicado: (2017)

Genetic Addiction Risk and Psychological Profiling Analyses for “Preaddiction” Severity Index
por: Blum, Kenneth, et al.
Publicado: (2022)

Critical Analysis of White House Anti-Drug Plan
por: Blum, Kenneth, et al.
Publicado: (2017)

How to Combat the Global Opioid Crisis
por: Dennen A., Catherine, et al.
Publicado: (2023)

Calvin klein (CK) designer cocktail, new “Speedball” is the “grimm reaper”: Brain dopaminergic surge a potential death sentence
por: Gold, Mark S, et al.
Publicado: (2020)

Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction
por: Blum, Kenneth, et al.
Publicado: (2015)

Hypersexuality Addiction and Withdrawal: Phenomenology, Neurogenetics and Epigenetics
por: Blum, Kenneth, et al.
Publicado: (2015)

Correction: Hypersexuality Addiction and Withdrawal: Phenomenology, Neurogenetics and Epigenetics
por: Blum, Kenneth, et al.
Publicado: (2015)

Retraction: Hypersexuality Addiction and Withdrawal: Phenomenology, Neurogenetics and Epigenetics
por: Blum, Kenneth, et al.
Publicado: (2015)

Hypersexuality Addiction and Withdrawal: Phenomenology, Neurogenetics and Epigenetics
por: Blum, Kenneth, et al.
Publicado: (2015)

Introducing Precision Addiction Management of Reward Deficiency Syndrome, the Construct That Underpins All Addictive Behaviors
por: Blum, Kenneth, et al.
Publicado: (2018)

Missing heritability, polygenic scores, and gene–environment correlation
por: Plomin, Robert
Publicado: (2013)

Americas’ opioid/psychostimulant epidemic would benefit from general population early identification of genetic addiction risk especially in children of alcoholics (COAs)
por: Blum, K, et al.
Publicado: (2019)

Hypothesizing Nutrigenomic-Based Precision Anti-Obesity Treatment and Prophylaxis: Should We Be Targeting Sarcopenia Induced Brain Dysfunction?
por: Blum, Kenneth, et al.
Publicado: (2021)

Improving naltrexone compliance and outcomes with putative pro- dopamine regulator KB220, compared to treatment as usual
por: Blum, Kenneth, et al.
Publicado: (2020)

“Dopamine homeostasis” requires balanced polypharmacy: Issue with destructive, powerful dopamine agents to combat America’s drug epidemic
por: Blum, Kenneth, et al.
Publicado: (2017)

Evidence for the DRD2 Gene as a Determinant of Reward Deficiency Syndrome (RDS)
por: Blum, Kenneth, et al.
Publicado: (2023)

Reward Deficiency Syndrome (RDS): A Cytoarchitectural Common Neurobiological Trait of All Addictions
por: Blum, Kenneth, et al.
Publicado: (2021)

Hypothesizing Las Vegas and Sutherland Springs Mass Shooters Suffer from Reward Deficiency Syndrome: “Born Bad”
por: McLaughlin, Thomas, et al.
Publicado: (2017)

Would induction of dopamine homeostasis via coupling genetic addiction risk score (GARS®) and pro-dopamine regulation benefit benzodiazepine use disorder (BUD)?
por: Blum, K, et al.
Publicado: (2018)

Genetic Addiction Risk Severity Assessment Identifies Polymorphic Reward Genes as Antecedents to Reward Deficiency Syndrome (RDS) Hypodopaminergia’s Effect on Addictive and Non-Addictive Behaviors in a Nuclear Family
por: Dennen, Catherine A., et al.
Publicado: (2022)

The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA
por: Cui, Jing, et al.
Publicado: (2014)

Functionally-informed fine-mapping and polygenic localization of complex trait heritability
por: Weissbrod, Omer, et al.
Publicado: (2020)

Pro-Dopamine Regulator (KB220) A Fifty Year Sojourn to Combat Reward Deficiency Syndrome (RDS): Evidence Based Bibliography (Annotated)
por: Kenneth, Blum, et al.
Publicado: (2018)

Hypothesizing High Negative Emotionality as a Function of Genetic Addiction Risk Severity (GARS) Testing in Alcohol Use Disorder (AUD)
por: Blum, Kenneth, et al.
Publicado: (2020)

Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case–Control Subjects
por: Blum, Kenneth, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n1uek3vccfakgsstldaiar6lsb