Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria

The gut microbiota-dependent metabolite trimethylamine-N-oxide (TMAO) is linked to an increased risk for cardiovascular diseases. Trimethylamine (TMA), which is subsequently oxidized to TMAO in the liver, is formed by intestinal bacteria via distinct biochemical routes from dietary precursors that a...

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Detalles Bibliográficos
Autores principales: Rath, Silke, Rox, Katharina, Kleine Bardenhorst, Sven, Schminke, Ulf, Dörr, Marcus, Mayerle, Julia, Frost, Fabian, Lerch, Markus M., Karch, André, Brönstrup, Mark, Pieper, Dietmar H., Vital, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547441/
https://www.ncbi.nlm.nih.gov/pubmed/34519520
http://dx.doi.org/10.1128/mSystems.00945-21

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