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Inactivation of Nitrite-Dependent Nitric Oxide Biosynthesis Is Responsible for Overlapped Antibiotic Resistance between Naturally and Artificially Evolved Pseudomonas aeruginosa
Metabolic flexibility of Pseudomonas aeruginosa could lead to new strategies to combat bacterial infection. The present study used gas chromatography-mass spectrometry (GC-MS)-based metabolomics to investigate global metabolism in naturally and artificially evolved strains with cefoperazone-sulbacta...
Autores principales: | Kuang, Su-fang, Feng, Ding-yun, Chen, Zhuang-gui, Liang, Zhuo-zheng, Xiang, Juan-juan, Li, Hui, Peng, Xuan-xian, Zhang, Tiantuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547483/ https://www.ncbi.nlm.nih.gov/pubmed/34546070 http://dx.doi.org/10.1128/mSystems.00732-21 |
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