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Inactivation of Nitrite-Dependent Nitric Oxide Biosynthesis Is Responsible for Overlapped Antibiotic Resistance between Naturally and Artificially Evolved Pseudomonas aeruginosa

Metabolic flexibility of Pseudomonas aeruginosa could lead to new strategies to combat bacterial infection. The present study used gas chromatography-mass spectrometry (GC-MS)-based metabolomics to investigate global metabolism in naturally and artificially evolved strains with cefoperazone-sulbacta...

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Detalles Bibliográficos
Autores principales: Kuang, Su-fang, Feng, Ding-yun, Chen, Zhuang-gui, Liang, Zhuo-zheng, Xiang, Juan-juan, Li, Hui, Peng, Xuan-xian, Zhang, Tiantuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547483/
https://www.ncbi.nlm.nih.gov/pubmed/34546070
http://dx.doi.org/10.1128/mSystems.00732-21

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