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PD-L2 glycosylation promotes immune evasion and predicts anti-EGFR efficacy

BACKGROUND: Combination therapy has been explored for advanced head and neck squamous cell carcinoma (HNSCC) owing to the limited efficacy of anti-epidermal growth factor receptor (EGFR) therapy. Increased expression and glycosylation of immune checkpoint molecules in tumors are responsible for cetu...

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Detalles Bibliográficos
Autores principales:	Xu, Yiqi, Gao, Zhenyue, Hu, Ruxin, Wang, Yuqing, Wang, Yuhong, Su, Zheng, Zhang, Xiaoyue, Yang, Jingxuan, Mei, Mei, Ren, Yu, Li, Min, Zhou, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547513/ https://www.ncbi.nlm.nih.gov/pubmed/34697216 http://dx.doi.org/10.1136/jitc-2021-002699

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