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Immune landscape in vulvar cancer-draining lymph nodes indicates distinct immune escape mechanisms in support of metastatic spread and growth

BACKGROUND: Therapeutic immune intervention is highly dependent on the T-cell priming and boosting capacity of tumor-draining lymph nodes (TDLN). In vulvar cancer, in-depth studies on the immune status of (pre)metastatic TDLN is lacking. METHODS: We have phenotyped and enumerated various T-cell and...

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Detalles Bibliográficos
Autores principales:	Heeren, Anne Marijne, Rotman, Jossie, Samuels, Sanne, Zijlmans, Henry J M A A, Fons, Guus, van de Vijver, Koen K, Bleeker, Maaike C G, Kenter, Gemma G, Jordanova, Ekaterina J, de Gruijl, Tanja D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547515/ https://www.ncbi.nlm.nih.gov/pubmed/34697217 http://dx.doi.org/10.1136/jitc-2021-003623

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