A rapid, simple and sensitive LC-MS/MS method for lenvatinib quantification in human plasma for therapeutic drug monitoring

Lenvatinib (LENVA) is an oral antineoplastic drug used for the treatment of hepatocellular carcinoma and thyroid carcinoma. LENVA therapeutic drug monitoring (TDM) should be mandatory for a precision medicine to optimize the drug dosage. To this end, the development of a sensitive and robust quantif...

Descripción completa

Detalles Bibliográficos
Autores principales: Zanchetta, Martina, Iacuzzi, Valentina, Posocco, Bianca, Bortolin, Giorgia, Poetto, Ariana Soledad, Orleni, Marco, Canil, Giovanni, Guardascione, Michela, Foltran, Luisa, Fanotto, Valentina, Puglisi, Fabio, Gagno, Sara, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547652/
https://www.ncbi.nlm.nih.gov/pubmed/34699578
http://dx.doi.org/10.1371/journal.pone.0259137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547652/
https://www.ncbi.nlm.nih.gov/pubmed/34699578
http://dx.doi.org/10.1371/journal.pone.0259137

Ejemplares similares