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Risk factors assessment for radiographically guided port implantations with forearm access

INTRODUCTION: Port implantations at the forearm are associated with an increased risk of relevant vein thrombosis. Therefore, with this study we sought to identify the responsible risk factors to improve technical quality of the method. METHODS: This is a retrospective analysis of 313 patients with...

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Autores principales: Nadjiri, Jonathan, Geith, Tobias, Waggershauser, Tobias, Forster, Stephan, Paprottka, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547706/
https://www.ncbi.nlm.nih.gov/pubmed/34699565
http://dx.doi.org/10.1371/journal.pone.0259127
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author Nadjiri, Jonathan
Geith, Tobias
Waggershauser, Tobias
Forster, Stephan
Paprottka, Philipp
author_facet Nadjiri, Jonathan
Geith, Tobias
Waggershauser, Tobias
Forster, Stephan
Paprottka, Philipp
author_sort Nadjiri, Jonathan
collection PubMed
description INTRODUCTION: Port implantations at the forearm are associated with an increased risk of relevant vein thrombosis. Therefore, with this study we sought to identify the responsible risk factors to improve technical quality of the method. METHODS: This is a retrospective analysis of 313 patients with port implantation at the forearm in 2019. Then, exploratory statistics were conducted comprising Cox-Regression and Kaplan-Meier-Analyses. RESULTS: Mean age was 60 ± 14 years. 232 (74%) of the patients were female. No early infection was observed. 29 late infections and 57 cases of thrombosis occurred. In only 9% of the patients with thrombosis hospital admission was necessary for treatment. Median interval to the diagnosis of thrombosis was 23 days; inter-quartile-range: 16–75. Mean interval to elective port explantation was 227 ± 128 days. There was no effect of occurrence of thrombosis of the interventionalist, the assistance nor of several technical aspects. However, there was a significantly lower risk of thrombosis for primary implanted port system compared to replacement ports, Hazard-ratio: 0.34 [Confidence interval: 0.172, 0.674], p = 0.002. Age was a significant risk factor for late infections, Hazard-ratio: 3.35 [Confidence interval:1.84, 6.07], p < 0.0001. CONCLUSION: The main risk factor for adverse outcome after radiographically guided port implantation at the forearm is the type of the implanted port system. The reason for that might not be the material itself but the experience of a team with a certain port system. Age is a risk factor for late complications.
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spelling pubmed-85477062021-10-27 Risk factors assessment for radiographically guided port implantations with forearm access Nadjiri, Jonathan Geith, Tobias Waggershauser, Tobias Forster, Stephan Paprottka, Philipp PLoS One Research Article INTRODUCTION: Port implantations at the forearm are associated with an increased risk of relevant vein thrombosis. Therefore, with this study we sought to identify the responsible risk factors to improve technical quality of the method. METHODS: This is a retrospective analysis of 313 patients with port implantation at the forearm in 2019. Then, exploratory statistics were conducted comprising Cox-Regression and Kaplan-Meier-Analyses. RESULTS: Mean age was 60 ± 14 years. 232 (74%) of the patients were female. No early infection was observed. 29 late infections and 57 cases of thrombosis occurred. In only 9% of the patients with thrombosis hospital admission was necessary for treatment. Median interval to the diagnosis of thrombosis was 23 days; inter-quartile-range: 16–75. Mean interval to elective port explantation was 227 ± 128 days. There was no effect of occurrence of thrombosis of the interventionalist, the assistance nor of several technical aspects. However, there was a significantly lower risk of thrombosis for primary implanted port system compared to replacement ports, Hazard-ratio: 0.34 [Confidence interval: 0.172, 0.674], p = 0.002. Age was a significant risk factor for late infections, Hazard-ratio: 3.35 [Confidence interval:1.84, 6.07], p < 0.0001. CONCLUSION: The main risk factor for adverse outcome after radiographically guided port implantation at the forearm is the type of the implanted port system. The reason for that might not be the material itself but the experience of a team with a certain port system. Age is a risk factor for late complications. Public Library of Science 2021-10-26 /pmc/articles/PMC8547706/ /pubmed/34699565 http://dx.doi.org/10.1371/journal.pone.0259127 Text en © 2021 Nadjiri et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Nadjiri, Jonathan
Geith, Tobias
Waggershauser, Tobias
Forster, Stephan
Paprottka, Philipp
Risk factors assessment for radiographically guided port implantations with forearm access
title Risk factors assessment for radiographically guided port implantations with forearm access
title_full Risk factors assessment for radiographically guided port implantations with forearm access
title_fullStr Risk factors assessment for radiographically guided port implantations with forearm access
title_full_unstemmed Risk factors assessment for radiographically guided port implantations with forearm access
title_short Risk factors assessment for radiographically guided port implantations with forearm access
title_sort risk factors assessment for radiographically guided port implantations with forearm access
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547706/
https://www.ncbi.nlm.nih.gov/pubmed/34699565
http://dx.doi.org/10.1371/journal.pone.0259127
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