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PD-1 checkpoint blockade enhances adoptive immunotherapy by human Vγ2Vδ2 T cells against human prostate cancer

Human Vγ2Vδ2 (also termed Vγ9Vδ2) T cells play important roles in microbial and tumor immunity by monitoring foreign- and self-prenyl pyrophosphate metabolites in isoprenoid biosynthesis. Accumulation of isoprenoid metabolites after bisphosphonate treatment allows Vγ2Vδ2 T cells to recognize and kil...

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Detalles Bibliográficos
Autores principales:	Nada, Mohanad H., Wang, Hong, Hussein, Auter J., Tanaka, Yoshimasa, Morita, Craig T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547840/ https://www.ncbi.nlm.nih.gov/pubmed/34712512 http://dx.doi.org/10.1080/2162402X.2021.1989789

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