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Huaiqihuang (HQH) granule alleviates cyclophosphamide-induced nephrotoxicity via suppressing the MAPK/NF-κB pathway and NLRP3 inflammasome activation

CONTEXT: Severe nephrotoxicity greatly limits the clinical use of the common effective chemotherapeutic agent cyclophosphamide (CYP). Huaiqihuang (HQH) is a Chinese herbal complex with various pharmacological activities, widely used for treating kidney disease. OBJECTIVE: This study estimates the pr...

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Detalles Bibliográficos
Autores principales: Zhang, Yueming, Chang, Jian, Gao, Huan, Qu, Xiaoyu, Zhai, Jinghui, Tao, Lina, Sun, Jingmeng, Song, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547856/
https://www.ncbi.nlm.nih.gov/pubmed/34693876
http://dx.doi.org/10.1080/13880209.2021.1990356

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