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Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment

The global health crisis and economic tolls of COVID-19 necessitate a panoply of strategies to treat SARS-CoV-2 infection. To date, few treatment options exist, although neutralizing antibodies against the spike glycoprotein have proven to be effective. Because infection is initiated at the mucosa a...

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Detalles Bibliográficos
Autores principales: White, Ian, Tamot, Ninkka, Doddareddy, Rajitha, Ho, Jason, Jiao, Qun, Harvilla, Paul B., Yang, Tong-Yuan, Geist, Brian, Borrok, M. Jack, Truppo, Matthew D., Ganesan, Rajkumar, Chowdhury, Partha, Zwolak, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547864/
https://www.ncbi.nlm.nih.gov/pubmed/34693867
http://dx.doi.org/10.1080/19420862.2021.1987180