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Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment
The global health crisis and economic tolls of COVID-19 necessitate a panoply of strategies to treat SARS-CoV-2 infection. To date, few treatment options exist, although neutralizing antibodies against the spike glycoprotein have proven to be effective. Because infection is initiated at the mucosa a...
Autores principales: | White, Ian, Tamot, Ninkka, Doddareddy, Rajitha, Ho, Jason, Jiao, Qun, Harvilla, Paul B., Yang, Tong-Yuan, Geist, Brian, Borrok, M. Jack, Truppo, Matthew D., Ganesan, Rajkumar, Chowdhury, Partha, Zwolak, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547864/ https://www.ncbi.nlm.nih.gov/pubmed/34693867 http://dx.doi.org/10.1080/19420862.2021.1987180 |
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