Hypercoagulability of COVID-19 and Neurological Complications: A Review

The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognit...

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Autores principales: Moore, Patrick, Esmail, Fatema, Qin, Shuai, Nand, Sucha, Berg, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547944/
https://www.ncbi.nlm.nih.gov/pubmed/34763262
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2021.106163
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author Moore, Patrick
Esmail, Fatema
Qin, Shuai
Nand, Sucha
Berg, Stephanie
author_facet Moore, Patrick
Esmail, Fatema
Qin, Shuai
Nand, Sucha
Berg, Stephanie
author_sort Moore, Patrick
collection PubMed
description The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination.
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spelling pubmed-85479442021-10-27 Hypercoagulability of COVID-19 and Neurological Complications: A Review Moore, Patrick Esmail, Fatema Qin, Shuai Nand, Sucha Berg, Stephanie J Stroke Cerebrovasc Dis Review Article The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination. Elsevier Inc. 2022-01 2021-10-26 /pmc/articles/PMC8547944/ /pubmed/34763262 http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2021.106163 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Moore, Patrick
Esmail, Fatema
Qin, Shuai
Nand, Sucha
Berg, Stephanie
Hypercoagulability of COVID-19 and Neurological Complications: A Review
title Hypercoagulability of COVID-19 and Neurological Complications: A Review
title_full Hypercoagulability of COVID-19 and Neurological Complications: A Review
title_fullStr Hypercoagulability of COVID-19 and Neurological Complications: A Review
title_full_unstemmed Hypercoagulability of COVID-19 and Neurological Complications: A Review
title_short Hypercoagulability of COVID-19 and Neurological Complications: A Review
title_sort hypercoagulability of covid-19 and neurological complications: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547944/
https://www.ncbi.nlm.nih.gov/pubmed/34763262
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2021.106163
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