Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload

Myopalladin (MYPN) is a striated muscle-specific immunoglobulin domain-containing protein located in the sarcomeric Z-line and I-band. MYPN gene mutations are causative for dilated (DCM), hypertrophic, and restrictive cardiomyopathy. In a yeast two-hybrid screening, MYPN was found to bind to titin i...

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Detalles Bibliográficos
Autores principales: Filomena, Maria Carmela, Yamamoto, Daniel L, Carullo, Pierluigi, Medvedev, Roman, Ghisleni, Andrea, Piroddi, Nicoletta, Scellini, Beatrice, Crispino, Roberta, D'Autilia, Francesca, Zhang, Jianlin, Felicetta, Arianna, Nemska, Simona, Serio, Simone, Tesi, Chiara, Catalucci, Daniele, Linke, Wolfgang A, Polishchuk, Roman, Poggesi, Corrado, Gautel, Mathias, Bang, Marie-Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547954/
https://www.ncbi.nlm.nih.gov/pubmed/34558411
http://dx.doi.org/10.7554/eLife.58313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547954/
https://www.ncbi.nlm.nih.gov/pubmed/34558411
http://dx.doi.org/10.7554/eLife.58313

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