Robust Immune Response Induced by Schistosoma mansoni TSP-2 Antigen Coupled to Bacterial Outer Membrane Vesicles

PURPOSE: The use of adjuvants can significantly strengthen a vaccine’s efficacy. We sought to explore the immunization efficacy of bacterial outer membrane vesicles (OMVs) displaying the Schistosoma mansoni antigen, SmTSP-2, through a biotin-rhizavidin coupling approach. The rationale is to exploit...

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Detalles Bibliográficos
Autores principales: Barbosa, Mayra M F, Kanno, Alex I, Barazzone, Giovana C, Rodriguez, Dunia, Pancakova, Violeta, Trentini, Monalisa, Faquim-Mauro, Eliana L, Freitas, Amanda P, Khouri, Mariana I, Lobo-Silva, Jessica, Goncalves, Viviane M, Schenkman, Rocilda P F, Tanizaki, Martha M, Boraschi, Diana, Malley, Richard, Farias, Leonardo P, Leite, Luciana C C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548026/
https://www.ncbi.nlm.nih.gov/pubmed/34712047
http://dx.doi.org/10.2147/IJN.S315786

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