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Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil

Species of the genus Lippia are rich in essential oils and have shown antibacterial properties, which may be related to oils' chemical composition. The present work aimed to evaluate the antimicrobial potential of Lippia origanoides Kunth against two bacteria strains: Escherichia coli and Staph...

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Autores principales: Ribeiro, Fabiana Paiva, Santana de Oliveira, Mozaniel, de Oliveira Feitosa, André, Santana Barbosa Marinho, Patricia, Moacir do Rosario Marinho, Andrey, de Aguiar Andrade, Eloisa Helena, Favacho Ribeiro, Alcy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548111/
https://www.ncbi.nlm.nih.gov/pubmed/34712353
http://dx.doi.org/10.1155/2021/9930336
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author Ribeiro, Fabiana Paiva
Santana de Oliveira, Mozaniel
de Oliveira Feitosa, André
Santana Barbosa Marinho, Patricia
Moacir do Rosario Marinho, Andrey
de Aguiar Andrade, Eloisa Helena
Favacho Ribeiro, Alcy
author_facet Ribeiro, Fabiana Paiva
Santana de Oliveira, Mozaniel
de Oliveira Feitosa, André
Santana Barbosa Marinho, Patricia
Moacir do Rosario Marinho, Andrey
de Aguiar Andrade, Eloisa Helena
Favacho Ribeiro, Alcy
author_sort Ribeiro, Fabiana Paiva
collection PubMed
description Species of the genus Lippia are rich in essential oils and have shown antibacterial properties, which may be related to oils' chemical composition. The present work aimed to evaluate the antimicrobial potential of Lippia origanoides Kunth against two bacteria strains: Escherichia coli and Staphylococcus aureus. Leaf essential oils were obtained by hydrodistillation in a modified Clevenger-type apparatus, and their chemical composition was determined by gas chromatography coupled to mass spectrometry (GC/MS) and flame ionization detection (GC/FID). We identified 28 compounds, representing 98.87% of the total concentration of the essential oil. The compounds identified at the highest concentrations were 1,8-cineole (35.04%), carvacrol (11.32%), p-cymene (8.53%), α-pinene (7.17%), and γ-terpinene (7.16%). The leaf essential oil of L. origanoides showed antibacterial action on biological isolates of Escherichia coli and Staphylococcus aureus. For Escherichia coli, the oil presented bactericidal action at concentrations of 5–20 μL/mL. Regarding Staphylococcus aureus, the bactericidal effect was noted at 20 μL/mL and the bacteriostatic action was noted around 2.5–10 μL/mL. Given the results obtained, L. origanoides essential oil showed promising biological potential against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria, thus encouraging further studies on substances isolated from this species to contribute to the development of new antimicrobial drugs.
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spelling pubmed-85481112021-10-27 Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil Ribeiro, Fabiana Paiva Santana de Oliveira, Mozaniel de Oliveira Feitosa, André Santana Barbosa Marinho, Patricia Moacir do Rosario Marinho, Andrey de Aguiar Andrade, Eloisa Helena Favacho Ribeiro, Alcy Evid Based Complement Alternat Med Research Article Species of the genus Lippia are rich in essential oils and have shown antibacterial properties, which may be related to oils' chemical composition. The present work aimed to evaluate the antimicrobial potential of Lippia origanoides Kunth against two bacteria strains: Escherichia coli and Staphylococcus aureus. Leaf essential oils were obtained by hydrodistillation in a modified Clevenger-type apparatus, and their chemical composition was determined by gas chromatography coupled to mass spectrometry (GC/MS) and flame ionization detection (GC/FID). We identified 28 compounds, representing 98.87% of the total concentration of the essential oil. The compounds identified at the highest concentrations were 1,8-cineole (35.04%), carvacrol (11.32%), p-cymene (8.53%), α-pinene (7.17%), and γ-terpinene (7.16%). The leaf essential oil of L. origanoides showed antibacterial action on biological isolates of Escherichia coli and Staphylococcus aureus. For Escherichia coli, the oil presented bactericidal action at concentrations of 5–20 μL/mL. Regarding Staphylococcus aureus, the bactericidal effect was noted at 20 μL/mL and the bacteriostatic action was noted around 2.5–10 μL/mL. Given the results obtained, L. origanoides essential oil showed promising biological potential against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria, thus encouraging further studies on substances isolated from this species to contribute to the development of new antimicrobial drugs. Hindawi 2021-10-19 /pmc/articles/PMC8548111/ /pubmed/34712353 http://dx.doi.org/10.1155/2021/9930336 Text en Copyright © 2021 Fabiana Paiva Ribeiro et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ribeiro, Fabiana Paiva
Santana de Oliveira, Mozaniel
de Oliveira Feitosa, André
Santana Barbosa Marinho, Patricia
Moacir do Rosario Marinho, Andrey
de Aguiar Andrade, Eloisa Helena
Favacho Ribeiro, Alcy
Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
title Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
title_full Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
title_fullStr Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
title_full_unstemmed Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
title_short Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
title_sort chemical composition and antibacterial activity of the lippia origanoides kunth essential oil from the carajás national forest, brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548111/
https://www.ncbi.nlm.nih.gov/pubmed/34712353
http://dx.doi.org/10.1155/2021/9930336
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