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Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil
Species of the genus Lippia are rich in essential oils and have shown antibacterial properties, which may be related to oils' chemical composition. The present work aimed to evaluate the antimicrobial potential of Lippia origanoides Kunth against two bacteria strains: Escherichia coli and Staph...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548111/ https://www.ncbi.nlm.nih.gov/pubmed/34712353 http://dx.doi.org/10.1155/2021/9930336 |
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author | Ribeiro, Fabiana Paiva Santana de Oliveira, Mozaniel de Oliveira Feitosa, André Santana Barbosa Marinho, Patricia Moacir do Rosario Marinho, Andrey de Aguiar Andrade, Eloisa Helena Favacho Ribeiro, Alcy |
author_facet | Ribeiro, Fabiana Paiva Santana de Oliveira, Mozaniel de Oliveira Feitosa, André Santana Barbosa Marinho, Patricia Moacir do Rosario Marinho, Andrey de Aguiar Andrade, Eloisa Helena Favacho Ribeiro, Alcy |
author_sort | Ribeiro, Fabiana Paiva |
collection | PubMed |
description | Species of the genus Lippia are rich in essential oils and have shown antibacterial properties, which may be related to oils' chemical composition. The present work aimed to evaluate the antimicrobial potential of Lippia origanoides Kunth against two bacteria strains: Escherichia coli and Staphylococcus aureus. Leaf essential oils were obtained by hydrodistillation in a modified Clevenger-type apparatus, and their chemical composition was determined by gas chromatography coupled to mass spectrometry (GC/MS) and flame ionization detection (GC/FID). We identified 28 compounds, representing 98.87% of the total concentration of the essential oil. The compounds identified at the highest concentrations were 1,8-cineole (35.04%), carvacrol (11.32%), p-cymene (8.53%), α-pinene (7.17%), and γ-terpinene (7.16%). The leaf essential oil of L. origanoides showed antibacterial action on biological isolates of Escherichia coli and Staphylococcus aureus. For Escherichia coli, the oil presented bactericidal action at concentrations of 5–20 μL/mL. Regarding Staphylococcus aureus, the bactericidal effect was noted at 20 μL/mL and the bacteriostatic action was noted around 2.5–10 μL/mL. Given the results obtained, L. origanoides essential oil showed promising biological potential against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria, thus encouraging further studies on substances isolated from this species to contribute to the development of new antimicrobial drugs. |
format | Online Article Text |
id | pubmed-8548111 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-85481112021-10-27 Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil Ribeiro, Fabiana Paiva Santana de Oliveira, Mozaniel de Oliveira Feitosa, André Santana Barbosa Marinho, Patricia Moacir do Rosario Marinho, Andrey de Aguiar Andrade, Eloisa Helena Favacho Ribeiro, Alcy Evid Based Complement Alternat Med Research Article Species of the genus Lippia are rich in essential oils and have shown antibacterial properties, which may be related to oils' chemical composition. The present work aimed to evaluate the antimicrobial potential of Lippia origanoides Kunth against two bacteria strains: Escherichia coli and Staphylococcus aureus. Leaf essential oils were obtained by hydrodistillation in a modified Clevenger-type apparatus, and their chemical composition was determined by gas chromatography coupled to mass spectrometry (GC/MS) and flame ionization detection (GC/FID). We identified 28 compounds, representing 98.87% of the total concentration of the essential oil. The compounds identified at the highest concentrations were 1,8-cineole (35.04%), carvacrol (11.32%), p-cymene (8.53%), α-pinene (7.17%), and γ-terpinene (7.16%). The leaf essential oil of L. origanoides showed antibacterial action on biological isolates of Escherichia coli and Staphylococcus aureus. For Escherichia coli, the oil presented bactericidal action at concentrations of 5–20 μL/mL. Regarding Staphylococcus aureus, the bactericidal effect was noted at 20 μL/mL and the bacteriostatic action was noted around 2.5–10 μL/mL. Given the results obtained, L. origanoides essential oil showed promising biological potential against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria, thus encouraging further studies on substances isolated from this species to contribute to the development of new antimicrobial drugs. Hindawi 2021-10-19 /pmc/articles/PMC8548111/ /pubmed/34712353 http://dx.doi.org/10.1155/2021/9930336 Text en Copyright © 2021 Fabiana Paiva Ribeiro et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Ribeiro, Fabiana Paiva Santana de Oliveira, Mozaniel de Oliveira Feitosa, André Santana Barbosa Marinho, Patricia Moacir do Rosario Marinho, Andrey de Aguiar Andrade, Eloisa Helena Favacho Ribeiro, Alcy Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil |
title | Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil |
title_full | Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil |
title_fullStr | Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil |
title_full_unstemmed | Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil |
title_short | Chemical Composition and Antibacterial Activity of the Lippia origanoides Kunth Essential Oil from the Carajás National Forest, Brazil |
title_sort | chemical composition and antibacterial activity of the lippia origanoides kunth essential oil from the carajás national forest, brazil |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548111/ https://www.ncbi.nlm.nih.gov/pubmed/34712353 http://dx.doi.org/10.1155/2021/9930336 |
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