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GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation

Spinal cord injury (SCI) refers to a major worldwide cause of accidental death and disability. However, the complexity of the pathophysiological mechanism can result in less-effective clinical treatment. Growth differentiation factor 11 (GDF-11), an antiageing factor, was reported to affect the deve...

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Detalles Bibliográficos
Autores principales: Xu, Yu, Hu, Xinli, Li, Feida, Zhang, Haojie, Lou, Junsheng, Wang, Xingyu, Wang, Hui, Yin, Lingyan, Ni, Wenfei, Kong, Jianzhong, Wang, Xiangyang, Li, Yao, Zhou, Kailiang, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548157/
https://www.ncbi.nlm.nih.gov/pubmed/34712387
http://dx.doi.org/10.1155/2021/8186877