HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7

Chd7 encodes an ATP-dependent chromatin remodeler which has been shown to target specific genomic loci and alter local transcription potentially by remodeling chromatin structure. De novo mutations in CHD7 are the major cause of CHARGE syndrome which features multiple developmental defects. We exami...

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Detalles Bibliográficos
Autores principales: Hsieh, Fu-Kai, Ji, Fei, Damle, Manashree, Sadreyev, Ruslan I, Kingston, Robert E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548210/
https://www.ncbi.nlm.nih.gov/pubmed/34663690
http://dx.doi.org/10.26508/lsa.202101127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548210/
https://www.ncbi.nlm.nih.gov/pubmed/34663690
http://dx.doi.org/10.26508/lsa.202101127

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