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HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7
Chd7 encodes an ATP-dependent chromatin remodeler which has been shown to target specific genomic loci and alter local transcription potentially by remodeling chromatin structure. De novo mutations in CHD7 are the major cause of CHARGE syndrome which features multiple developmental defects. We exami...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548210/ https://www.ncbi.nlm.nih.gov/pubmed/34663690 http://dx.doi.org/10.26508/lsa.202101127 |