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A brain-specific pgc1α fusion transcript affects gene expression and behavioural outcomes in mice
PGC1α is a transcriptional coactivator in peripheral tissues, but its function in the brain remains poorly understood. Various brain-specific Pgc1α isoforms have been reported in mice and humans, including two fusion transcripts (FTs) with non-coding repetitive sequences, but their function is unkno...
Autores principales: | Lozoya, Oswaldo A, Xu, Fuhua, Grenet, Dagoberto, Wang, Tianyuan, Stevanovic, Korey D, Cushman, Jesse D, Hagler, Thomas B, Gruzdev, Artiom, Jensen, Patricia, Hernandez, Bairon, Riadi, Gonzalo, Moy, Sheryl S, Santos, Janine H, Woychik, Richard P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548212/ https://www.ncbi.nlm.nih.gov/pubmed/34649938 http://dx.doi.org/10.26508/lsa.202101122 |
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