Structural basis for protein glutamylation by the Legionella pseudokinase SidJ

Legionella pneumophila (LP) avoids phagocytosis by secreting nearly 300 effector proteins into the host cytosol. SidE family of effectors (SdeA, SdeB, SdeC and SidE) employ phosphoribosyl ubiquitination to target multiple host Rab GTPases and innate immune factors. To suppress the deleterious toxici...

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Detalles Bibliográficos
Autores principales: Adams, Michael, Sharma, Rahul, Colby, Thomas, Weis, Felix, Matic, Ivan, Bhogaraju, Sagar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548325/
https://www.ncbi.nlm.nih.gov/pubmed/34702826
http://dx.doi.org/10.1038/s41467-021-26429-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548325/
https://www.ncbi.nlm.nih.gov/pubmed/34702826
http://dx.doi.org/10.1038/s41467-021-26429-y

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