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Accurate prediction of protein torsion angles using evolutionary signatures and recurrent neural network

The amino acid sequence of a protein contains all the necessary information to specify its shape, which dictates its biological activities. However, it is challenging and expensive to experimentally determine the three-dimensional structure of proteins. The backbone torsion angles play a critical ro...

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Detalles Bibliográficos
Autores principales: Xu, Yong-Chang, ShangGuan, Tian-Jun, Ding, Xue-Ming, Cheung, Ngaam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548351/
https://www.ncbi.nlm.nih.gov/pubmed/34702851
http://dx.doi.org/10.1038/s41598-021-00477-2