The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation

Aging is a natural and progressive process characterized by an increased frequency of age-related diseases such as cancer. But its mechanism is unclear. TNFAIP8L2 (Tipe2) is an important negative regulator for homeostasis through inhibiting TLR and TCR signaling. Our work reveals that Tipe2 might ha...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Na, Ma, Chao, Xu, Wenwen, Jin, Guiyuan, Zheng, Yi, Zhang, Lei, Liu, Bingyu, Gao, Chengjiang, Liu, Suxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548391/
https://www.ncbi.nlm.nih.gov/pubmed/34702807
http://dx.doi.org/10.1038/s41419-021-04289-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548391/
https://www.ncbi.nlm.nih.gov/pubmed/34702807
http://dx.doi.org/10.1038/s41419-021-04289-0

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