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The Effect of the APOE-ε4 Allele on the Cholinergic Circuitry for Subjects With Different Levels of Cognitive Impairment
Background: Cholinergic deficiency has been suggested to associate with the abnormal accumulation of Aβ and tau for patients with Alzheimer's disease (AD). However, no studies have investigated the effect of APOE-ε4 and group differences in modulating the cholinergic basal forebrain–amygdala ne...
Autores principales: | Lai, Ying-Liang Larry, Chen, Kuan, Lee, Tzu-Wei, Tso, Chao-Wei, Lin, Hui-Hsien, Kuo, Li-Wei, Chen, Cheng-Yu, Liu, Hua-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548434/ https://www.ncbi.nlm.nih.gov/pubmed/34721251 http://dx.doi.org/10.3389/fneur.2021.651388 |
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