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The Effect of the APOE-ε4 Allele on the Cholinergic Circuitry for Subjects With Different Levels of Cognitive Impairment

Background: Cholinergic deficiency has been suggested to associate with the abnormal accumulation of Aβ and tau for patients with Alzheimer's disease (AD). However, no studies have investigated the effect of APOE-ε4 and group differences in modulating the cholinergic basal forebrain–amygdala ne...

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Detalles Bibliográficos
Autores principales: Lai, Ying-Liang Larry, Chen, Kuan, Lee, Tzu-Wei, Tso, Chao-Wei, Lin, Hui-Hsien, Kuo, Li-Wei, Chen, Cheng-Yu, Liu, Hua-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548434/
https://www.ncbi.nlm.nih.gov/pubmed/34721251
http://dx.doi.org/10.3389/fneur.2021.651388

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