Molecular profiling of advanced solid tumours. The impact of experimental molecular-matched therapies on cancer patient outcomes in early-phase trials: the MAST study

INTRODUCTION: Molecular-matched therapies have revolutionized cancer treatment. We evaluated the improvement in clinical outcomes of applying an in-house customized Next Generation Sequencing panel in a single institution. METHODS: Patients with advanced solid tumors were molecularly selected to rec...

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Detalles Bibliográficos
Autores principales: Gambardella, Valentina, Lombardi, Pasquale, Carbonell-Asins, Juan Antonio, Tarazona, Noelia, Cejalvo, Juan Miguel, González-Barrallo, Inés, Martín-Arana, Jorge, Tébar-Martínez, Roberto, Viala, Alba, Bruixola, Gema, Hernando, Cristina, Blasco, Inma, Papaccio, Federica, Martínez-Ciarpaglini, Carolina, Alfaro-Cervelló, Clara, Seda-García, Enrique, Blesa, Sebastián, Chirivella, Isabel, Castillo, Josefa, Montón-Bueno, José Vicente, Roselló, Susana, Huerta, Marisol, Pérez-Fidalgo, Alejandro, Martín-Martorell, Paloma, Insa-Mollá, Amelia, Fleitas, Tania, Rentero-Garrido, Pilar, Zúñiga-Trejos, Sheila, Cervantes, Andrés, Roda, Desamparados
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548537/
https://www.ncbi.nlm.nih.gov/pubmed/34493820
http://dx.doi.org/10.1038/s41416-021-01502-x

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