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Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine
Cancer precision medicine (CPM) could tailor the best treatment for individual cancer patients, while imaging techniques play important roles in its application. With the characteristics of noninvasion, nonionized, radiation-free, multidimensional imaging function, and real-time monitoring, magnetic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548572/ https://www.ncbi.nlm.nih.gov/pubmed/34722253 http://dx.doi.org/10.3389/fonc.2021.707618 |
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author | Liu, Xiaoman Rong, Pengfei |
author_facet | Liu, Xiaoman Rong, Pengfei |
author_sort | Liu, Xiaoman |
collection | PubMed |
description | Cancer precision medicine (CPM) could tailor the best treatment for individual cancer patients, while imaging techniques play important roles in its application. With the characteristics of noninvasion, nonionized, radiation-free, multidimensional imaging function, and real-time monitoring, magnetic resonance imaging (MRI) is an effective way for early tumor detection, and it has become a tower of strength in CPM imaging techniques. Due to linkage with nephrogenic systemic fibrosis (NSF), gadolinium (Gd)-based contrast agent (CA), which was long used in MRI, has been restricted by the Food and Drug Administration (FDA). In this review, we would like to introduce the manganese (Mn)-based CAs that could significantly increase the safety of MRI CAs by realizing more superior performance and functions simultaneously in the diagnosis and treatment of tumors. Also, recent advances in Mn-based hybrid nanomaterials for CPM are summarized and discussed. |
format | Online Article Text |
id | pubmed-8548572 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85485722021-10-28 Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine Liu, Xiaoman Rong, Pengfei Front Oncol Oncology Cancer precision medicine (CPM) could tailor the best treatment for individual cancer patients, while imaging techniques play important roles in its application. With the characteristics of noninvasion, nonionized, radiation-free, multidimensional imaging function, and real-time monitoring, magnetic resonance imaging (MRI) is an effective way for early tumor detection, and it has become a tower of strength in CPM imaging techniques. Due to linkage with nephrogenic systemic fibrosis (NSF), gadolinium (Gd)-based contrast agent (CA), which was long used in MRI, has been restricted by the Food and Drug Administration (FDA). In this review, we would like to introduce the manganese (Mn)-based CAs that could significantly increase the safety of MRI CAs by realizing more superior performance and functions simultaneously in the diagnosis and treatment of tumors. Also, recent advances in Mn-based hybrid nanomaterials for CPM are summarized and discussed. Frontiers Media S.A. 2021-10-13 /pmc/articles/PMC8548572/ /pubmed/34722253 http://dx.doi.org/10.3389/fonc.2021.707618 Text en Copyright © 2021 Liu and Rong https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Liu, Xiaoman Rong, Pengfei Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine |
title | Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine |
title_full | Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine |
title_fullStr | Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine |
title_full_unstemmed | Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine |
title_short | Recent Advances of Manganese-Based Hybrid Nanomaterials for Cancer Precision Medicine |
title_sort | recent advances of manganese-based hybrid nanomaterials for cancer precision medicine |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548572/ https://www.ncbi.nlm.nih.gov/pubmed/34722253 http://dx.doi.org/10.3389/fonc.2021.707618 |
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