Deficiency of lung-specific claudin-18 leads to aggravated infection with Cryptococcus deneoformans through dysregulation of the microenvironment in lungs

Cryptococcus deneoformans is an opportunistic fungal pathogen that infects the lungs via airborne transmission and frequently causes fatal meningoencephalitis. Claudins (Cldns), a family of proteins with 27 members found in mammals, form the tight junctions within epithelial cell sheets. Cldn-4 and...

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Detalles Bibliográficos
Autores principales: Sato, Ko, Matsumoto, Ikumi, Suzuki, Koya, Tamura, Atsushi, Shiraishi, Aki, Kiyonari, Hiroshi, Kasamatsu, Jun, Yamamoto, Hideki, Miyasaka, Tomomitsu, Tanno, Daiki, Miyahara, Anna, Zong, Tong, Kagesawa, Takafumi, Oniyama, Akiho, Kawamura, Kotone, Kitai, Yuki, Umeki, Aya, Kanno, Emi, Tanno, Hiromasa, Ishii, Keiko, Tsukita, Sachiko, Kawakami, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548597/
https://www.ncbi.nlm.nih.gov/pubmed/34702961
http://dx.doi.org/10.1038/s41598-021-00708-6

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