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Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis
Osteoarthritis (OA) is a common degenerative joint disease featuring the degeneration, destruction, and ossification of cartilage. Inflammation which may facilitate OA occurrence and development is considered as the main pathological factor. Betulin, a natural product extracted from birch bark, has...
Autores principales: | Ren, Chenghao, Jin, Jie, Hu, Wei, Chen, Qi, Yang, Jian, Wu, Yaosen, Zhou, Yifei, Sun, Liaojun, Gao, Weiyang, Zhang, Xiaolei, Tian, Naifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548689/ https://www.ncbi.nlm.nih.gov/pubmed/34721040 http://dx.doi.org/10.3389/fphar.2021.754038 |
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