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Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1

TGF-β-centered epithelial-mesenchymal transition (EMT) is a key process involved in radiation-induced pulmonary injury (RIPI) and pulmonary fibrosis. PIEZO1, a mechanosensitive calcium channel, is expressed in myeloid cell and has been found to play an important role in bleomycin-induced pulmonary f...

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Detalles Bibliográficos
Autores principales:	Huang, Jia-Qi, Zhang, Hao, Guo, Xue-Wei, Lu, Yan, Wang, Si-Nian, Cheng, Bo, Dong, Su-He, Lyu, Xiao-Li, Li, Feng-Sheng, Li, Yong-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548710/ https://www.ncbi.nlm.nih.gov/pubmed/34722630 http://dx.doi.org/10.3389/fmolb.2021.725275

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