Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This r...

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Detalles Bibliográficos
Autores principales: Sandroni, Claudio, Cronberg, Tobias, Sekhon, Mypinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Narrative Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548866/
https://www.ncbi.nlm.nih.gov/pubmed/34705079
http://dx.doi.org/10.1007/s00134-021-06548-2
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author Sandroni, Claudio
Cronberg, Tobias
Sekhon, Mypinder
author_facet Sandroni, Claudio
Cronberg, Tobias
Sekhon, Mypinder
author_sort Sandroni, Claudio
collection PubMed
description Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested strategies for outcome prediction.
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spelling pubmed-85488662021-10-27 Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis Sandroni, Claudio Cronberg, Tobias Sekhon, Mypinder Intensive Care Med Narrative Review Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested strategies for outcome prediction. Springer Berlin Heidelberg 2021-10-27 2021 /pmc/articles/PMC8548866/ /pubmed/34705079 http://dx.doi.org/10.1007/s00134-021-06548-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Narrative Review
Sandroni, Claudio
Cronberg, Tobias
Sekhon, Mypinder
Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
title Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
title_full Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
title_fullStr Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
title_full_unstemmed Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
title_short Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
title_sort brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
topic Narrative Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548866/
https://www.ncbi.nlm.nih.gov/pubmed/34705079
http://dx.doi.org/10.1007/s00134-021-06548-2
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